Nano-Precision Mechano-Biology Group

Bringing nanoscale techniques
toward single-molecule mechanobiology

Biology is coordinated interactions of molecules. We investigate the mechanics of biological systems with nanoscale approaches at the single-molecule level. We employ existing techniques like molecular tweezers, fluorescence imaging, and nano/microfabrication, and develop new methods when necessary.


    • 2021/06 | Dr. Cha receives a postdoctoral grant from NRF. Congratulations!
    • 2021/05 | Dr. Shon's work on SNARE-recycling NSF proteins (previously conducted at SNU) is published in Nature Communications.
      We applied magnetic tweezers to observe the millisecond-scale disassembly of SNAREs at high spatiotemporal resolutions. Find out more: Link
    • 2021/04 | The first film on Shon Lab is just released: Link (I-Bio production)
    • 2021/03 | Dr. Sang-Hyun Rah joins the lab as a postdoctoral fellow. He obtained his PhD in Physics from KAIST and previously worked at TU Delft. Dr. Rah will be conducting research on synaptic membrane proteins. Welcome!
    • 2021/02 | Dr. Sang-Hyun Rah has been awarded the prestigious PIURI Postdoctoral Fellowship. Congratulations! See: 포스텍
    • 2020/11 | Our lab receives the 1st BioDrone Award from MDimune! We will be conducting research on cell-derived nano-vesicles. See: 매일경제, 네이버
    • 2020/10 | Prof. Shon is now jointly appointed as a faculty member of I-Bio. We welcome people from both physics and biology!
    • 2020/09 | Dr. Minkwon Cha joins the lab as a postdoc. He was trained in single-molecule biophysics during his PhD at KAIST/SNU. He also knows how to handle wild cats. Welcome!